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I may not be postulating this right, but the \ B12 and B9 are so inter-related

It also plays an essential role in folate and related one-carbon metabolism, where FAD is required as a cofactor for methylenetetrahydrofolate reductase (MTHFR), a key folate-metabolizing enzyme

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Quantitative real-time PCR(RT-PCR) was performed on a ViiATM 7 RT-PCR system (Applied Biosystems Inc.) with SYBR-green ChamQTM SYBR Color qPCR Master Mix (Vazyme)